Ramune is a doctor who specializes in treating patients with "mystery diseases," which are caused when something "strange" sneaks into the hearts of the weak-minded. He is a foul-mouthed physician who is rude to most and very rarely understands the atmosphere around him. Though, he is a very skilled doctor who can quickly identify the root cause of any strange illness. But because he always puts his patients first, he tries not to treat them too harshly.